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Medicinal Chemistry – hit identification, hit to lead, lead optimisation, SAR, physical property optimisation, new chemical space.
Route Scouting – Fast & responsive design and test approach, De-novo route design, integrating innovative modern technologies, cost optimisation, scale-up viability, sustainability & green chemistry.
Natural Products & 3D Scaffolds – Complex target total synthesis, enantio- & diastereocontrol, step/cost efficiency,
Fee for Service – Custom synthesis, stable isotopic labelling, bespoke reagents/building blocks/catalysts.
Consulting & Problem Solving – Ideas generation, route analysis & design, critical assessment, viability checks, knowledge guided solutions.
Our mission is to deliver the highest quality synthetic chemistry services to our clients.
Originally a spin-out from the University of Oxford, we have roots in world-leading research and translate these academic discoveries into solutions for industrial problems. We cultivate a proactive and responsive approach to ideas generation, implementation and problem solving.
We have unparalleled speed and success rate in our projects, and go above and beyond in overcoming challenges.
A novel sulfinylamine reagent for the one-pot do novo synthesis of structurally diverse medicinally relevant sulfonimidamides from widely available nucleophilic organometallic reagents and amines.
A novel sulfinylamine reagent for the two-stage synthesis of diverse sulfondiimines and sulfoximines via organometallic reagent addition followed by catalysed imination or oxidation of the sulfilimine intermediate.
A novel sulfinylhydroxylamine reagent for the one-pot rapid and scalable synthesis of a diverse range of sulfoximines and sulfonimidamides from Grignard or organolithium reagents and amine nucleophiles.
A novel sulfinylamine reagent for the one-step rapid and scalable synthesis of medicinally relevant primary sulfonamides from a diverse range of aliphatic, aromatic and heteroaromatic Grignard and organolithium reagents.
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