Cortex Organics
Accelerating Discovery Through Great Chemistry.
Delivering elite custom synthesis, problem solving and route scouting services for the most demanding pharmaceutical and agrochemical projects.
Cortex Chemistry
Our Services
Medicinal Chemistry – hit identification, hit to lead, lead optimisation, SAR, physical property optimisation, new chemical space.
Route Scouting – Fast & responsive design and test approach, De-novo route design, integrating innovative modern technologies, cost optimisation, scale-up viability, sustainability & green chemistry.
Natural Products & 3D Scaffolds – Complex target total synthesis, enantio- & diastereocontrol, step/cost efficiency.
Fee for Service – Custom synthesis, stable isotopic labelling, bespoke reagents/building blocks/catalysts.
Consulting & Problem Solving – Ideas generation, route analysis & design, critical assessment, viability checks, knowledge guided solutions.
Cortex Mission
Value added at
every step
Our mission is to deliver the highest quality synthetic chemistry services to our clients.
Originally a spin-out from the University of Oxford, we have roots in world-leading research and translate these academic discoveries into solutions for industrial problems. We cultivate a proactive and responsive approach to ideas generation, implementation and problem solving.
We have unparalleled speed and success rate in our projects, and go above and beyond in overcoming challenges.
Cortex Mission
reagents for
organic synthesis
TrNSO
A novel sulfinylamine reagent for the one-pot de novo synthesis of structurally diverse medicinally relevant sulfonimidamides from widely available nucleophilic organometallic reagents and amines.
t-OctNSO
A novel sulfinylamine reagent for the two-stage synthesis of diverse sulfonimidines and sulfoximines via organometallic reagent addition followed by catalysed imination or oxidation of the sulfimiline intermediate.
BiPhONSO
A novel sulfinylhydroxylamine reagent for the one-pot rapid and scalable synthesis of a diverse range of sulfoximines and sulfonimidamides from Grignard or organolithium reagents and amine nucleophiles.
TrNSO
A novel sulfinylamine reagent for the one-step rapid and scalable synthesis of medicinally relevant primary sulfonamides from a diverse range of aliphatic, aromatic and heteroaromatic Grignard and organolithium reagents.